Day 1 :
Sechenov University, Moscow Engineering Physical University (MEPhI) and National Alliance for Translational Medicine, Russian Federation
Keynote: Personalized healthcare services and innovative tools to manage chronic disorders and cardiac failures and to secure health
Time : 9:30 - 10:10
Sergey Suchkov was born in the City of Astrakhan, Russia, in a dynasty of medical doctors, graduated from Astrakhan State Medical University and was awarded with MD. Then he maintained his PhD and Doctor’s Degree. And later was working for Helmholtz Eye Research Institute and Moscow Regional Clinical Research Institute (MONIKI). Dr Suchkov was a Secretary-in-Chief of the Editorial Board, Biomedical Science, an international journal published jointly by the USSR Academy of Sciences and the Royal Society of Chemistry, UK. At present, Dr Sergey Suchkov is: (i) a Director, Center for Personalized Medicine, Sechenov University, (ii) Chair, Dept for Translational Medicine, Moscow Engineering Physical University (MAPhI), and (iii) Secretary General, United Cultural Convention (UCC), Cambridge, UK. A Member of the: New York
Academy of Sciences, American Chemical Society (ACS), American Heart Association (AHA), AMEE, Dundee, UK; EPMA, Brussels, EU; PMC, Washington, DC, USA and ISPM, Tokyo, Japan.
A new systems approach to diseased states and wellness result in a new branch in the healthcare services, namely, personalized medicine (PM). To achieve the implementation of PM concept into the daily practice including clinical cardiology, it is necessary to create a fundamentally new strategy based upon the subclinical recognition of bio indicators (biopredictors and biomarkers) of hidden abnormalities long before the disease clinically manifests itself. Each decision-maker values the impact of their decision to use PM on their own budget and well-being, which may not necessarily be optimal for society as a whole. It would be extremely useful to integrate data harvesting from different databanks for applications such as prediction and personalization of further treatment to thus provide more tailored measures for the patients and persons-at-risk resulting in improved outcomes whilst securing the healthy state and wellness, reduced adverse events, and more cost effective use of health care resources. One of the most advanced areas in cardiology is atherosclerosis, cardiovascular and coronary disorders as well as in yocarditis. A lack of medical guidelines has been identified by the majority of responders as the predominant barrier for adoption, indicating a need for the development of best practices and guidelines to support the implementation of PM into the daily practice of cardiologists! Implementation of PM requires a lot before the current model “physician-patient” could be gradually displaced by a new model “medical advisor-healthy person-at-risk”. This is the reason for developing.
San Bortolo Hospital, Italy
Time : 10:10-10:50
Marco Picichè is graduated with a degree in medicine from the University of Florence in 1995 and completed his cardiac surgery residency at the Tor Vergata University of Rome in 2000, both summa cum laude. He has worked as an Assistant at Saint Luc Hospital, Catholic University of Louvain, Brussels (1999–2001), as a Clinic Head/Hospital Assistant at the universities of Clermont-Ferrand (2003–2004) and Montpellier (2004–2007). He held regular teaching appointments at the University of Montpellier School of Medicine, obtained certification by the French Board in cardiac surgery (Paris, 2007), earned his research master in Surgical Science (Paris, 2007). In Canada he authored a research project on Noncoronary collateral circulation, which was submitted to the annual research competition at Québec Heart and Lung Institute, Laval University, and received the competition’s highest grant. In September 2011 he received a doctor of philosophy (PhD) in therapeutic innovations from Paris-Sud University. He is the Editor in Chief of the book: Dawn and evolution of cardiac procedures: research avenues in cardiac surgery and interventional cardiology. Currently he is a Consultant Cardiac Surgeon in Italy
The policy of transfusion in cardiac surgery has changed dramatically over the last decade. After years of almost anarchic management, relying upon local experiences, the Society of Thoracic Surgeons and the Association of Cardiovascular Anesthesiologists have set precious guidelines for transfusion in Cardiac Surgery, in 2007 and in 2011. The history of transfusion is fascinating. Humans recognized over time that the loss of blood was associated with weakness and death. Older history of blood transfusion based on the traditional idea of blood being the ‘living force’ of the body. Mystical fascination with the properties of blood shows some remnants even today, manifesting itself via such terms as ‘hot blooded’, ‘bad blood’, ‘cold blood’. After centuries of almost absent evolution, a great step forward took place only in the 21st century, with the introduction of sterile methodologies (Pasteur, Semmelweiss), the discovery of the ABO blood group system (Landois and Landsteiner), and the development of practical anticoagulation. Nowadays, evidence-based guidelines are an attempt to reconcile conflicting lines of evidence, giving greater weight to evidence derived from more methodologically rigorous studies and those for which the overall weight of evidence is most convincing. Although they must be viewed as guidelines and recommendations, not absolutes, they have become a very useful tool in daily practice, and underline the importance of teamwork in the management of blood transfusion.
Sarajevo University Clinical Center, Bosnia and Herzegovina
Time : 11:05-11:45
Sekib Sokolovic is Professor of Internal Medicine at Medical Faculty and University Clinical Center Sarajevo. He is European Hypertension Specialist and his expertise is in evaluation in improving the health and wellbeing for cardiovascular patients. His interest is open and contextual evaluation model based on systemic microcirculation as well as on macrocirculation including arterial hypertension, pulmonary arterial hypertension, arterial stiffness and vitamin D. He has great experience in clinical research and teaching both in hospital and education institutions and invited speaker in the major scientific medical events worldwide.
The Nailfold Capilaroscopy (NFC) is non-invasive simple diagnostic tool in a detection of microcirculation abnormalities in certain disorders like rheumatic diseases, Raynaud’s phenomena (RP), cardiovascular diseases including coronary arterial diseases, arterial hypertension and pulmonary arterial hypertension, diabetes mellitus etc. The correlation between the pulmonary arterial hypertension (PAH) and capillary changes have well been documented. Antiphospholipid syndrome (APS) with its microbleeding spots can be visualized in the nailbed. The morfology of the capillaries in the nailfold area are well visualized by the video nailfold capillaroscopy (NFC). Arterial hypertension is characterized by reduced capillary density and dilatation of either afferent limb, efferent limb, apex or all of it together. The coronary slow phenomenon (CSP) is also associated with nailfold capillary changes. The NFC may detect dilatation of capillaries, tortuosity and microhemorrhage that reflect coronary microcirculation pathology.